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STAT6 抗体 (pTyr641)

STAT6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3020502
发货至: 中国
  • 抗原 See all STAT6 抗体
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    抗原表位
    • 27
    • 16
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr641
    适用
    • 122
    • 70
    • 59
    • 10
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    宿主
    • 103
    • 18
    • 4
    • 1
    克隆类型
    • 100
    • 25
    多克隆
    标记
    • 71
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This STAT6 antibody is un-conjugated
    应用范围
    • 64
    • 44
    • 43
    • 27
    • 26
    • 24
    • 18
    • 18
    • 13
    • 9
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    产品特性
    Phosphorylated Antibodies
    免疫原
    A phospho specific peptide corresponding to residues surrounding Y641 of human STAT6
    亚型
    IgG
    Top Product
    Discover our top product STAT6 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Shen, Li, You, Wu, Wu, Zhao, Zhu, Guo, Li, Li, Ma, Yang, Chen: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).

  • 抗原
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    别名
    STAT6 (STAT6 产品)
    别名
    D12S1644 antibody, IL-4-STAT antibody, STAT6B antibody, STAT6C antibody, signal transducer and activator of transcription 6 antibody, signal transducer and activator of transcription 6-like antibody, STAT6 antibody, Stat6 antibody, LOC100859543 antibody
    背景
    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.,D12S1644,IL-4-STAT,STAT6B,STAT6C,STAT6,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Protein phosphorylation,STAT6
    分子量
    74 kDa/81 kDa/94 kDa
    基因ID
    6778
    UniProt
    P42226
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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