Leptin 抗体
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- 抗原 See all Leptin (LEP) 抗体
- Leptin (LEP)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Leptin antibody is un-conjugated
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应用范围
- ELISA
- 特异性
- Recognizes human leptin, a 16kD hormone that plays a key role in homeostasis, in energy intake and expenditure. It is produced by fat cells and the placenta. Leptin is a well known marker for obesity, the amount of leptin in the circulation correlates with the amount of fat tissue. Lack of functional leptin and leptin receptors lead to morbid obesity. However, leptin resistance is present in almost all obese humans, meaning that obesity is not necessarily due to a decrease in leptin, but rather to a decrease in the amount of leptin that reaches and binds to the leptin receptors in the hypothalamus. Leptin has also been implicated in a number of other processes including immune function, neuroendocrine function, the adaptive response to fasting, blood pressure, bone formation, blood cell development, glucose homeostasis, fatty acid metabolism and reproductive function. May be used as a capture antibody in ELISA assays for leptin.
- 纯化方法
- Affinity purified
- 免疫原
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Recombinant Leptin.
Type of Immunogen: Recombinant protein - 克隆位点
- 3G7
- 亚型
- IgG1
- Top Product
- Discover our top product LEP Primary Antibody
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- 应用备注
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Approved: ELISA
Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA together with LS-C58411 as a detection reagent. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Short term: -20°C
Long term: -20°C.
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- 抗原
- Leptin (LEP)
- 别名
- Leptin (LEP 产品)
- 别名
- ob antibody, obese antibody, LEPD antibody, OB antibody, OBS antibody, leptin antibody, Lep antibody, LEP antibody, lep antibody
- 背景
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Name/Gene ID: LEP
Synonyms: LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB - 基因ID
- 3952
- UniProt
- P41159
- 途径
- JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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