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Leptin 抗体

LEP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3G7 unconjugated
产品编号 ABIN294985
发货至: 中国
  • 抗原 See all Leptin (LEP) 抗体
    Leptin (LEP)
    适用
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    宿主
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    小鼠
    克隆类型
    • 171
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    单克隆
    标记
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    This Leptin antibody is un-conjugated
    应用范围
    • 126
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    ELISA
    特异性
    Recognizes human leptin, a 16kD hormone that plays a key role in homeostasis, in energy intake and expenditure. It is produced by fat cells and the placenta. Leptin is a well known marker for obesity, the amount of leptin in the circulation correlates with the amount of fat tissue. Lack of functional leptin and leptin receptors lead to morbid obesity. However, leptin resistance is present in almost all obese humans, meaning that obesity is not necessarily due to a decrease in leptin, but rather to a decrease in the amount of leptin that reaches and binds to the leptin receptors in the hypothalamus. Leptin has also been implicated in a number of other processes including immune function, neuroendocrine function, the adaptive response to fasting, blood pressure, bone formation, blood cell development, glucose homeostasis, fatty acid metabolism and reproductive function. May be used as a capture antibody in ELISA assays for leptin.
    纯化方法
    Affinity purified
    免疫原
    Recombinant Leptin.

    Type of Immunogen: Recombinant protein
    克隆位点
    3G7
    亚型
    IgG1
    Top Product
    Discover our top product LEP Primary Antibody
  • 应用备注
    Approved: ELISA

    Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA together with LS-C58411 as a detection reagent.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Short term: -20°C
    Long term: -20°C.
  • 抗原
    Leptin (LEP)
    别名
    Leptin (LEP 产品)
    别名
    ob antibody, obese antibody, LEPD antibody, OB antibody, OBS antibody, leptin antibody, Lep antibody, LEP antibody, lep antibody
    背景
    Name/Gene ID: LEP

    Synonyms: LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB
    基因ID
    3952
    UniProt
    P41159
    途径
    JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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