Endocytic receptors Cubilin and Megalin are colocalized in the renal proximal tubule. Among the ligandsare vitamin transcobalamin(TC)-B12, vitamin D-binding protein(DBP), albumin, apolipoprotein (apoA-I) etc. From the fact renal failure is accompanied by the dysfunction of Cubilin, Cubilin is expected to involvethe disease development of kidney.This antibody was established from the purified serum of rabbits immunized with partial peptide of rat Cubilin. This antibody is useful for Western blotting.