Aurora-A (Aurora-A/STK-15/Aik) encoding a centrosome-associated kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. So that, Aurora-A is a potentialoncogene. Aurora family have been identified three types (Aurora-A, B, C) which has high homologydomain in C terminal region. Aurora family is indispensable kinase that regulate the structure and functionof centrosomes and spindle. Aurora-A could be one of targeting molecule of anti-cancer therapy.This antibody was established from the purified serum of the immunized rabbit with N terminal region ofAurora-A and did not show any cross- reactivity to Aurora-B and Aurora-C. This antibody is useful forwestern blotting and immunohistochemistry.