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LYVE1 抗体

LYVE1 适用: 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN289493
发货至: 中国
  • 抗原 See all LYVE1 抗体
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    适用
    • 68
    • 57
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 76
    • 6
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 77
    • 12
    多克隆
    标记
    • 53
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LYVE1 antibody is un-conjugated
    应用范围
    • 77
    • 32
    • 31
    • 21
    • 18
    • 10
    • 10
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    Protein A affinity chromatography
    免疫原
    LYVE1 antibody was raised in rabbit using recombinant mouse soluble Lyve-1 as the immunogen.
    亚型
    IgG
    Top Product
    Discover our top product LYVE1 Primary Antibody
  • 应用备注
    ELISA: 1-15 µg/mL, FC: 3-10 µg/mL, WB:2-5 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Supplied in lyophilized formin PBS buffer
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Piao, Xiong, Li, Saxena, Smith, Hippen, Paluskievicz, Willsonshirkey, Blazar, Abdi, Bromberg: "Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration." in: Cell reports, Vol. 30, Issue 4, pp. 1052-1062.e5, (2020) (PubMed).

    Bourland, Fradette, Auger: "Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development." in: Scientific reports, Vol. 8, Issue 1, pp. 13191, (2019) (PubMed).

    Piao, Xiong, Famulski, Brinkman, Li, Toney, Wagner, Saxena, Simon, Bromberg: "Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling." in: Nature communications, Vol. 9, Issue 1, pp. 3020, (2018) (PubMed).

    Le, Nowell, Kim-Fuchs, Botteri, Hiller, Ismail, Pimentel, Chai, Karnezis, Rotmensz, Renne, Gandini, Pouton, Ferrari, Möller, Stacker, Sloan: "Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination." in: Nature communications, Vol. 7, pp. 10634, (2016) (PubMed).

    Brinkman, Iwami, Hritzo, Xiong, Ahmad, Simon, Hippen, Blazar, Bromberg: "Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration." in: Nature communications, Vol. 7, pp. 12021, (2016) (PubMed).

    Stefanini, Paul, Robledo, Chan, Getz, Campbell, Kechele, Casari, Piatt, Caron, Mackman, Weyrich, Parrott, Boulaftali, Adams, Peters, Bergmeier: "RASA3 is a critical inhibitor of RAP1-dependent platelet activation." in: The Journal of clinical investigation, Vol. 125, Issue 4, pp. 1419-32, (2015) (PubMed).

    Owens, Pickup, Novitskiy, Giltnane, Gorska, Hopkins, Hong, Moses: "Inhibition of BMP signaling suppresses metastasis in mammary cancer." in: Oncogene, Vol. 34, Issue 19, pp. 2437-49, (2015) (PubMed).

    Yücel, Johnston, Ly, Patel, Drake, Gümüş, Fraenkl, Moore, Tobbia, Armstrong, Horvath, Gupta: "Identification of lymphatics in the ciliary body of the human eye: a novel "uveolymphatic" outflow pathway." in: Experimental eye research, Vol. 89, Issue 5, pp. 810-9, (2009) (PubMed).

  • 抗原
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    别名
    LYVE1 (LYVE1 产品)
    别名
    LYVE1 antibody, XLKD1 antibody, CRSBP-1 antibody, HAR antibody, LYVE-1 antibody, 1200012G08Rik antibody, Crsbp-1 antibody, Lyve-1 antibody, Xlkd1 antibody, lymphatic vessel endothelial hyaluronic receptor 1a antibody, lymphatic vessel endothelial hyaluronan receptor 1 antibody, lyve1a antibody, LYVE1 antibody, Lyve1 antibody
    背景
    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily.
    途径
    Glycosaminoglycan Metabolic Process
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