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RORA 抗体

KO Validated RORA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2857022
发货至: 中国
  • 抗原 See all RORA 抗体
    RORA (RAR-Related Orphan Receptor A (RORA))
    适用
    • 78
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    宿主
    • 73
    • 5
    克隆类型
    • 74
    • 4
    多克隆
    标记
    • 44
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    This RORA antibody is un-conjugated
    应用范围
    • 68
    • 28
    • 15
    • 11
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to ROR alpha (RAR-related orphan receptor A)
    ROR alpha antibody [N2N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ROR alpha. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse brain , HeLa , NIH-3T3

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Luo, Wang, Yeh, Sun, Liang, Xiao, Xu, Niu, Cheng, Maity, Jiang, Chang: "LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." in: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).

    Brożyna, Jóźwicki, Skobowiat, Jetten, Slominski: "RORα and RORγ expression inversely correlates with human melanoma progression." in: Oncotarget, Vol. 7, Issue 39, pp. 63261-63282, (2018) (PubMed).

  • 抗原
    RORA (RAR-Related Orphan Receptor A (RORA))
    别名
    RAR related orphan receptor A (RORA 产品)
    别名
    ror1 antibody, ror2 antibody, ror3 antibody, rzra antibody, nr1f1 antibody, MGC146531 antibody, NR1F1 antibody, ROR1 antibody, ROR2 antibody, ROR3 antibody, RZR-ALPHA antibody, RZRA antibody, RORalpha-B antibody, gb:dq017624 antibody, rora2 antibody, 9530021D13Rik antibody, Nr1f1 antibody, nmf267 antibody, sg antibody, staggerer antibody, tmgc26 antibody, RORalpha1 antibody, RAR related orphan receptor A antibody, RAR-related orphan receptor A antibody, RAR-related orphan receptor A, paralog a antibody, RAR-related orphan receptor alpha antibody, RORA antibody, rora antibody, Rora antibody, roraa antibody
    背景
    The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

    分子量
    63 kDa
    基因ID
    6095
    UniProt
    P35398
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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