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ARG2 抗体 (Center)

ARG2 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855753
发货至: 中国
  • 抗原 See all ARG2 抗体
    ARG2 (Arginase, Type II (ARG2))
    抗原表位
    • 19
    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Center
    适用
    • 51
    • 35
    • 16
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    宿主
    • 58
    • 11
    克隆类型
    • 60
    • 9
    多克隆
    标记
    • 37
    • 11
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARG2 antibody is un-conjugated
    应用范围
    • 63
    • 22
    • 22
    • 13
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 4
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Arginase II (arginase, type II)
    Arginase II antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ARG2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ARG2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: mouse kidney , 293T cytoplasm extract , NT2D1

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.32 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Polis, Srikanth, Gurevich, Gil-Henn, Samson: "L-Norvaline, a new therapeutic agent against Alzheimer's disease." in: Neural regeneration research, Vol. 14, Issue 9, pp. 1562-1572, (2019) (PubMed).

    Polis, Srikanth, Elliott, Gil-Henn, Samson: "L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 4, pp. 1036-1054, (2019) (PubMed).

  • 抗原
    ARG2 (Arginase, Type II (ARG2))
    别名
    arginase 2 (ARG2 产品)
    别名
    AII antibody, AU022422 antibody, zgc:65793 antibody, zgc:85630 antibody, wu:fb67g02 antibody, ARG2 antibody, LeARG2 antibody, arg1 antibody, arg3 antibody, arg2 antibody, arg2-c antibody, arg2-b antibody, arginase 2 antibody, arginase type II antibody, arginase 2 L homeolog antibody, arginase 2 S homeolog antibody, ARG2 antibody, Arg2 antibody, arg2 antibody, arg2.L antibody, arg2.S antibody
    背景
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

    Cellular Localization: Mitochondrion
    分子量
    39 kDa
    基因ID
    384
    UniProt
    P78540
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