XPC 抗体 (C-Term)
(1 reference)Quick Overview for XPC 抗体 (C-Term) (ABIN2855495)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 大鼠
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交叉反应 （详细）
- Rat (85 %)
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产品特性
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Rabbit Polyclonal antibody to XPC (xeroderma pigmentosum, complementation group C)
XPC antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human XPC. The exact sequence is proprietary.
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亚型
- IgG
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anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 700-940) antibody
XPC 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 141-250) antibodyXPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D11 unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 734-933) antibodyXPC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 734-933) antibodyXPC 适用: 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (HRP)XPC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (FITC)XPC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 141-250) antibodyXPC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: NT2D1 , IMR32 , U87-MG , MCF-7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.67 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).
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: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC
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背景
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This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Cellular Localization: Nucleus -
分子量
- 106 kDa
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基因ID
- 7508
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途径
- p53 Pathway, DNA Damage Repair
抗原
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