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TRAF1 抗体

This anti-TRAF1 antibody is a 兔 多克隆 antibody detecting TRAF1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2855374
发货至: 中国

Quick Overview for TRAF1 抗体 (ABIN2855374)

抗原

See all TRAF1 抗体
TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRAF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to TRAF1 (TNF receptor-associated factor 1)
    TRAF1 antibody [N1C1]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TRAF1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Raji

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.87 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

    别名

    TNF receptor associated factor 1

    背景

    The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.

    分子量

    46 kDa

    基因ID

    7185

    UniProt

    Q13077

    途径

    NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
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