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CCR5 抗体 (Center)

CCR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855010
发货至: 中国
  • 抗原 See all CCR5 抗体
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    抗原表位
    • 16
    • 13
    • 12
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 137
    • 40
    • 39
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 103
    • 29
    • 13
    • 4
    克隆类型
    • 106
    • 37
    • 3
    多克隆
    标记
    • 81
    • 15
    • 10
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CCR5 antibody is un-conjugated
    应用范围
    • 94
    • 66
    • 54
    • 20
    • 18
    • 17
    • 15
    • 14
    • 14
    • 13
    • 7
    • 4
    • 2
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    • 1
    Western Blotting (WB)
    产品特性
    Rabbit Polyclonal antibody to CCR5 (chemokine (C-C motif) receptor 5 (gene/pseudogene))
    CCR5 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human CCR5. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product CCR5 Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    说明

    Positive Control: U87-MG , SK-N-SH , IMR32 , Jurkat , Raji , NCI-H929

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    别名
    CCR5 (CCR5 产品)
    别名
    CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
    背景
    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Cell membrane
    分子量
    41 kDa
    基因ID
    1234
    途径
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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