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CCR5 抗体

CCR5 适用: 人, 大鼠 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 6G11D1 unconjugated
产品编号 ABIN5611203
发货至: 中国
  • 抗原 See all CCR5 抗体
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    适用
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    人, 大鼠
    宿主
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    小鼠
    克隆类型
    • 107
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    单克隆
    标记
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    This CCR5 antibody is un-conjugated
    应用范围
    • 94
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD195 (AA: extra mix) expressed in E. coli.
    克隆位点
    6G11D1
    亚型
    IgG1
    Top Product
    Discover our top product CCR5 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    别名
    CD195 (CCR5 产品)
    别名
    CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
    背景

    Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

    Aliases: CCR5, CKR5, CCR-5, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5

    分子量
    40.5 kDa
    基因ID
    1234
    HGNC
    1234
    途径
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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