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CENPF 抗体 (C-Term)

This anti-CENPF antibody is a 兔 多克隆 antibody detecting CENPF in WB, IHC (p), IF, ICC 和 IHC (wm). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854654
发货至: 中国

Quick Overview for CENPF 抗体 (C-Term) (ABIN2854654)

抗原

See all CENPF 抗体
CENPF (Centromere Protein F (CENPF))

适用

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宿主

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克隆类型

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多克隆

标记

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This CENPF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))
  • 抗原表位

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    C-Term

    交叉反应

    人, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to CENPF (centromere protein F, 350/400 kDa (mitosin))
    CENPF antibody [C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CENPF. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Raji

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chen, Lin, Cheng, Lin, Lo, Yen, Lee, Hsiao: "Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish." in: Oncotarget, Vol. 5, Issue 15, pp. 6300-11, (2015) (PubMed).

  • 抗原

    CENPF (Centromere Protein F (CENPF))

    别名

    centromere protein F

    背景

    This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

    Cellular Localization: Cytoplasm , perinuclear region , Nucleus matrix , Kinetochore , Spindle

    分子量

    368 kDa

    基因ID

    1063

    UniProt

    P49454

    途径

    Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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