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BRAF 抗体 (pThr400)

This anti-BRAF antibody is a 兔 多克隆 antibody detecting BRAF in DB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN389897
发货至: 中国

Quick Overview for BRAF 抗体 (pThr400) (ABIN389897)

抗原

See all BRAF 抗体
BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

适用

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宿主

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克隆类型

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多克隆

标记

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This BRAF antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB13721
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    pThr400

    特异性

    This Phospho-BRAF-pT400 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF.

    预测反应

    Mouse (Murine)

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF.

    亚型

    Ig Fraction
  • 应用备注

    DB = 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Duan, Cobb: "Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 51, pp. 22314-9, (2010) (PubMed).

  • 抗原

    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

    别名

    BRAF

    背景

    BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
    Synonyms: B-Raf proto-oncogene serine/threonine-protein kinase, p94, v-Raf murine sarcoma viral oncogene homolog B1

    分子量

    84437 DA

    基因ID

    673

    UniProt

    P15056

    途径

    MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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