HTRA2 抗体 (AA 355-458) (AbBy Fluor® 594)
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- 抗原 See all HTRA2 抗体
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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抗原表位
- AA 355-458
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HTRA2 antibody is conjugated to AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HtrA2
- 亚型
- IgG
- Top Product
- Discover our top product HTRA2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- 别名
- HtrA2/Omi (HTRA2 产品)
- 别名
- CG8464 antibody, DmHtrA2 antibody, Dmel\\CG8464 antibody, HtrA2/Omi antibody, Omi antibody, dOmi antibody, domi antibody, htrA2 antibody, omi antibody, HTRA2 antibody, PRSS25 antibody, OMI antibody, PARK13 antibody, AI481710 antibody, Prss25 antibody, mnd2 antibody, HTRA2-related serine protease antibody, HtrA serine peptidase 2 antibody, HtrA2 antibody, HTRA2 antibody, htra2 antibody, Htra2 antibody
- 背景
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Synonyms: High temperature requirement protein a2, HTRA 2, HtrA like serine protease, HtrA serine peptidase 2, Omi stress regulated endoprotease, PARK 13, PARK13, Protease serine 25, PRSS 25, PRSS25, Serine protease 25, Serine protease HTRA2 mitochondrial, HtrA2, HTRA2_HUMAN, mitochondrial, Omi stress-regulated endoprotease, Serine protease HTRA2, Serine proteinase OMI, Serine protease htra2 mitochondrial precursor, Serine protease omi.
Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.
- 基因ID
- 27429
- UniProt
- O43464
- 途径
- Positive Regulation of Endopeptidase Activity
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