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PROS1 抗体 (AA 245-295) (Alexa Fluor 594)

PROS 适用: 人, 大鼠, 小鼠 WB, IF (p) 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2805633
发货至: 中国
  • 抗原 See all PROS1 (PROS) 抗体
    PROS1 (PROS) (Protein S (PROS))
    抗原表位
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-295
    适用
    • 76
    • 23
    • 23
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 49
    • 11
    • 8
    • 7
    • 5
    克隆类型
    • 66
    • 14
    多克隆
    标记
    • 44
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PROS1 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 61
    • 31
    • 15
    • 12
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Protein S/PROS
    亚型
    IgG
    Top Product
    Discover our top product PROS Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PROS1 (PROS) (Protein S (PROS))
    别名
    Protein S (PROS 产品)
    别名
    PROS antibody, PS21 antibody, PS22 antibody, PS23 antibody, PS24 antibody, PS25 antibody, PSA antibody, THPH5 antibody, THPH6 antibody, zgc:154001 antibody, AW214361 antibody, protein S antibody, protein S (alpha) antibody, PROS1 antibody, Pros1 antibody, pros1 antibody
    背景

    Synonyms: Preproprotein S, Propiece of latent protein S, PROS 1, PROS, PROS_HUMAN, PROS1, Protein S alpha, Protein Sa, PS 21, PS 22, PS 23, PS 24, PS 25, PS 26, PS21, PS22, PS23, PS24, PS25, PS26, PSA, Vitamin K dependent protein S, Vitamin K-dependent protein S.

    Background: Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP), 60-70 % of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37 % of normal) correlates with severe recurrent venous thrombosis.

    基因ID
    5627
    UniProt
    P07225
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