BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 9-37), (N-Term) 抗体
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- 抗原 See all BRISC and BRCA1 A Complex Member 1 (BABAM1) 抗体
- BRISC and BRCA1 A Complex Member 1 (BABAM1)
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抗原表位
- AA 9-37, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Rabbit Anti-Human HSPC142 (N-term) Antibody
- 免疫原
- This HSPC142 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human HSPC142.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product BABAM1 Primary Antibody
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anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 1-329) antibody
BABAM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 36-85) antibodyBABAM1 适用: 人, 小鼠, 犬, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 116-143) antibodyBABAM1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20468 unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 9-37), (N-Term) antibodyBABAM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20467 unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (N-Term) antibodyBABAM1 适用: 人, 小鼠, 犬, 豚鼠, 马, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (Middle Region) antibodyBABAM1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100HSPC142 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- BRISC and BRCA1 A Complex Member 1 (BABAM1)
- 别名
- HSPC142 (BABAM1 产品)
- 别名
- merit40 antibody, nba1 antibody, zgc:100909 antibody, c19orf62 antibody, C19orf62 antibody, MERIT40 antibody, NBA1 antibody, C7H19orf62 antibody, 5430437P03Rik antibody, Merit40 antibody, BRISC and BRCA1 A complex member 1 antibody, BRISC and BRCA1 A complex member 1 L homeolog antibody, babam1 antibody, BABAM1 antibody, babam1.L antibody, Babam1 antibody
- 背景
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Target Description: HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. HSPC142 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36. component
Gene Symbol: BABAM1
- 分子量
- 36560 Da
- 基因ID
- 29086
- UniProt
- Q9NWV8
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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