BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 1-50) 抗体
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Quick Overview for BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 1-50) 抗体 (ABIN7452241)
抗原
See all BRISC and BRCA1 A Complex Member 1 (BABAM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-MERIT40 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 1 and 50
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亚型
- IgG
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anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 1-329) antibody
BABAM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 36-85) antibodyBABAM1 适用: 人, 小鼠, 犬, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 116-143) antibodyBABAM1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20468 unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 9-37), (N-Term) antibodyBABAM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20467 unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (Middle Region) antibodyBABAM1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (N-Term) antibodyBABAM1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7452241 has not performed satisfactorily when used for WB of MERIT40 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MERIT40.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BRISC and BRCA1 A Complex Member 1 (BABAM1)
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别名
- MERIT40
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背景
- Background: MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) Q9NWV8].
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基因ID
- 29086
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NCBI登录号
- NP_054892
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UniProt
- Q9NWV8
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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