PTPN21 抗体 (Center)
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- 抗原 See all PTPN21 抗体
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
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抗原表位
- AA 751-780, Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN21 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Rabbit Anti-Human PTPD1 (Center) Antibody
- 免疫原
- This PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PTPN21 Primary Antibody
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- 应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of anti-PTPD1 Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2.0 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
- 别名
- PTPD1 (PTPN21 产品)
- 别名
- PTPD1 antibody, PTPRL10 antibody, Ptp2E antibody, protein tyrosine phosphatase, non-receptor type 21 antibody, PTPN21 antibody, Ptpn21 antibody
- 背景
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Target Description: PTPD1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
Gene Symbol: PTPN21
- 分子量
- 133281 Da
- 基因ID
- 11099
- UniProt
- Q16825
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