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PTPN21 抗体 (Center)

PTPN21 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2793391
发货至: 中国
  • 抗原 See all PTPN21 抗体
    PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
    抗原表位
    • 15
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 751-780, Center
    适用
    • 29
    • 22
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 30
    克隆类型
    • 30
    多克隆
    标记
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPN21 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Rabbit Anti-Human PTPD1 (Center) Antibody
    免疫原
    This PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PTPN21 Primary Antibody
  • 应用备注
    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50Western blot analysis of anti-PTPD1 Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.0 mg/mL
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
    别名
    PTPD1 (PTPN21 产品)
    别名
    PTPD1 antibody, PTPRL10 antibody, Ptp2E antibody, protein tyrosine phosphatase, non-receptor type 21 antibody, PTPN21 antibody, Ptpn21 antibody
    背景

    Target Description: PTPD1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

    Gene Symbol: PTPN21

    分子量
    133281 Da
    基因ID
    11099
    UniProt
    Q16825
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