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TRAF1 抗体 (Middle Region)

This anti-TRAF1 antibody is a 兔 多克隆 antibody detecting TRAF1 in WB. Suitable for 人, 小鼠, Cow, 兔, 犬, 斑马鱼 和 马.
产品编号 ABIN2792210
发货至: 中国

Quick Overview for TRAF1 抗体 (Middle Region) (ABIN2792210)

抗原

See all TRAF1 抗体
TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

适用

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人, 小鼠, Cow, 兔, 犬, 斑马鱼, 马

宿主

  • 48
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  • 1

克隆类型

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  • 27
多克隆

标记

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This TRAF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    DAFRPDLSSA SFQRPQSETN VASGCPLFFP LSKLQSPKHA YVKDDTMFLK

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 84%

    产品特性

    This is a rabbit polyclonal antibody against TRAF1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TRAF1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 416 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

    别名

    TRAF1

    背景

    This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: EBI6, MGC:10353
    Protein Interaction Partner: ZNF662, KLHL38, TRIM42, RTP5, SSC5D, MORN3, POM121L4P, OLIG3, CCDC116, ZNF564, SLC25A48, ALS2CR11, LOC149950, ZNF417, TMC8, ZNF572, RBM45, C1orf216, ZNF440, TBC1D16, HAUS1, SYCE1, ZNF502, C5orf30, CCDC120, FBF1, ZNF587, BEX2, LCOR, FAM161A, PLEKHN1, RASSF
    Protein Size: 416

    分子量

    46 kDa

    基因ID

    7185

    NCBI登录号

    NM_005658, NP_005649

    UniProt

    Q13077

    途径

    NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
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