DIABLO 抗体 (C-Term)
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Quick Overview for DIABLO 抗体 (C-Term) (ABIN2792127)
抗原
See all DIABLO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- DIABLO Antibody - C-terminal region
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序列
- LVKLQVEEVH QLSRKAETKL AEAQIEELRQ KTQEEGEERA ESEQEAYLRE
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预测反应
- Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Pig: 85%
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产品特性
- This is a rabbit polyclonal antibody against DIABLO. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DIABLO
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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别名
- DIABLO
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背景
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Background Information: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
Gene Name: Diablo, IAP-binding mitochondrial protein
Alternative Symbols: SMAC, DFNA64
Protein Name: Diablo homolog (Drosophila) EMBL AAH95468.1
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分子量
- 21kDa
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基因ID
- 56616
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NCBI登录号
- NP_620308
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UniProt
- Q502X2
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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