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SLC7A5 抗体 (N-Term)

SLC7A5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789581
发货至: 中国
  • 抗原 See all SLC7A5 抗体
    SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
    抗原表位
    • 15
    • 4
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    • 1
    • 1
    • 1
    • 1
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    • 1
    N-Term
    适用
    • 31
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    • 15
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    • 3
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    • 2
    • 2
    宿主
    • 29
    • 2
    • 1
    克隆类型
    • 29
    • 3
    多克隆
    标记
    • 18
    • 1
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    • 1
    • 1
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    This SLC7A5 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 8
    • 6
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB)
    序列
    MAGAGPKRRA LAAPAAEEKE EAREKMLAAK SADGSAPAGE GEGVTLQRNI
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against SLC7A5. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product SLC7A5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 507 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
    别名
    SLC7A5 (SLC7A5 产品)
    别名
    4F2LC antibody, CD98 antibody, D16S469E antibody, E16 antibody, LAT1 antibody, MPE16 antibody, hLAT1 antibody, D0H16S474E antibody, TA1 antibody, JHI-21 antibody, SLC7A5 antibody, LAT-1 antibody, slc7a5a antibody, 4F2 antibody, 4F2HC antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mdu1 antibody, Mgp-2hc antibody, NACAE antibody, solute carrier family 7 member 5 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antibody, solute carrier family 7 member 5 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, SLC7A5 antibody, Slc7a5 antibody, slc7a5.S antibody, Slc3a2 antibody
    背景
    SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts.
    Alias Symbols: 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1
    Protein Interaction Partner: UBC, SUMO2, LGR4, NOS2, HNRNPU, ELAVL1, SLC3A2,
    Protein Size: 507
    分子量
    56 kDa
    基因ID
    8140
    NCBI登录号
    NM_003486, NP_003477
    UniProt
    Q01650
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