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SLC7A5 抗体 (C-Term)

SLC7A5 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265149
发货至: 中国
  • 抗原 See all SLC7A5 抗体
    SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
    抗原表位
    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 31
    • 16
    • 16
    • 15
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    • 3
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    • 2
    • 2
    人, 小鼠
    宿主
    • 29
    • 2
    • 1
    克隆类型
    • 29
    • 3
    多克隆
    标记
    • 18
    • 1
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    • 1
    • 1
    • 1
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    • 1
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    This SLC7A5 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 8
    • 5
    • 5
    • 4
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    SLC7A5 Antibody detects endogenous levels of total SLC7A5.
    预测反应
    Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human SLC7A5, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SLC7A5 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
    别名
    SLC7A5 (SLC7A5 产品)
    别名
    4F2LC antibody, CD98 antibody, D16S469E antibody, E16 antibody, LAT1 antibody, MPE16 antibody, hLAT1 antibody, D0H16S474E antibody, TA1 antibody, JHI-21 antibody, SLC7A5 antibody, LAT-1 antibody, slc7a5a antibody, 4F2 antibody, 4F2HC antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mdu1 antibody, Mgp-2hc antibody, NACAE antibody, solute carrier family 7 member 5 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antibody, solute carrier family 7 member 5 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, SLC7A5 antibody, Slc7a5 antibody, slc7a5.S antibody, Slc3a2 antibody
    背景

    Description: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts. When associated with LAPTM4B, recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation (PubMed:25998567).

    Gene: SLC7A5

    分子量
    55 kDa
    基因ID
    8140
    UniProt
    Q01650
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