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FCGR3A 抗体 (Middle Region)

FCGR3A 适用: 人, 大鼠, 小鼠, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789545
发货至: 中国
  • 抗原 See all FCGR3A 抗体
    FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
    抗原表位
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 64
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 豚鼠, 兔
    宿主
    • 49
    • 27
    克隆类型
    • 47
    • 28
    • 1
    多克隆
    标记
    • 31
    • 13
    • 11
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCGR3A antibody is un-conjugated
    应用范围
    • 45
    • 28
    • 22
    • 16
    • 13
    • 12
    • 8
    • 8
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB)
    序列
    DPIHLRCHSW KNTALHKVTY LQNGKGRKYF HHNSDFYIPK ATLKDSGSYF
    预测反应
    Guinea Pig: 79%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against FCGR3A. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product FCGR3A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 253 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
    别名
    FCGR3A (FCGR3A 产品)
    别名
    CD16 antibody, CD16A antibody, FCG3 antibody, FCGR3 antibody, FCGRIII antibody, FCR-10 antibody, FCRIII antibody, FCRIIIA antibody, IGFR3 antibody, Fcgr4 antibody, Fc fragment of IgG receptor IIIa antibody, FCGR3A antibody, Fcgr3a antibody
    背景
    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
    Protein Interaction Partner: SYK, ZBTB25, APP, IGHG1, GP6, SHC1, CD4, CD247, ZAP70, LCK, PTPRC, FCER1G, FCGR1A, CD38, APCS,
    Protein Size: 253
    分子量
    27 kDa
    基因ID
    2214
    NCBI登录号
    NM_001127596, NP_001121068
    UniProt
    P08637
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