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- 抗原 See all FCGR3A 抗体
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCGR3A antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 原理
- Mouse monoclonal antibody raised against native FCGR3A.
- 特异性
- This antibody reacts with CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA, 50-65 KDa, expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB, 48 KDa, mainly expressed on neutrophils).
- 交叉反应
- 人, Non-Human Primate
- 免疫原
- Native purified FCGR3A from normal human peripheral blood granulocytes.
- 克隆位点
- LNK16
- 亚型
- IgG1
- Top Product
- Discover our top product FCGR3A Primary Antibody
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- 应用备注
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Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In PBS (0.2 % BSA, 0.09 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
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Human macrophages kill human mesangial cells by Fas-L-induced apoptosis when triggered by antibody via CD16." in: Clinical and experimental immunology, Vol. 137, Issue 3, pp. 529-37, (2004) (PubMed).
: "IgE-mediated activation of NK cells through Fc gamma RIII." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 6, pp. 3054-8, (2003) (PubMed).
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Human macrophages kill human mesangial cells by Fas-L-induced apoptosis when triggered by antibody via CD16." in: Clinical and experimental immunology, Vol. 137, Issue 3, pp. 529-37, (2004) (PubMed).
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- 抗原
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- 别名
- FCGR3A (FCGR3A 产品)
- 别名
- CD16 antibody, CD16A antibody, FCG3 antibody, FCGR3 antibody, FCGRIII antibody, FCR-10 antibody, FCRIII antibody, FCRIIIA antibody, IGFR3 antibody, Fcgr4 antibody, Fc fragment of IgG receptor IIIa antibody, FCGR3A antibody, Fcgr3a antibody
- 基因ID
- 2214
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