HLAG 抗体 (C-Term)
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北京 101111
Quick Overview for HLAG 抗体 (C-Term) (ABIN2789375)
抗原
See all HLAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- HLA-G Antibody - C-terminal region
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序列
- HPVFDYEATL RCWALGFYPA EIILTWQRDG EDQTQDVELV ETRPAGDGTF
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预测反应
- Cow: 93%, Human: 100%, Pig: 93%
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产品特性
- This is a rabbit polyclonal antibody against HLA-G. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63107-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
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别名
- HLA-G
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背景
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Background Information: HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Gene Name: Major histocompatibility complex, class I, G
Alternative Symbols: MHC-G
Protein Name: HLA class I histocompatibility antigen, alpha chain G
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分子量
- 36kDa
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基因ID
- 3135
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NCBI登录号
- NP_002118
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UniProt
- P17693
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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