HLA-DOB 抗体 (N-Term)
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- 抗原 See all HLA-DOB 抗体
- HLA-DOB (Major Histocompatibility Complex, Class II, DO beta (HLA-DOB))
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抗原表位
- N-Term
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适用
- 人, Pig, 兔, 绵羊, Cow, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DOB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LTRLDSSMTQ GTDSPEDFVI QAKADCYFTN GTEKVQFVVR FIFNLEEYVR
- 预测反应
- Cow: 79%, Dog: 93%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 86%, Sheep: 86%
- 产品特性
- This is a rabbit polyclonal antibody against HLA-DOB. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human HLA-DOB
- Top Product
- Discover our top product HLA-DOB Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) antibody
HLA-DOB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) (AA 1-273) antibodyHLA-DOB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) (AA 1-273) antibodyHLA-DOB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) (N-Term) antibodyHLA-DOB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) antibodyHLA-DOB 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) (AA 27-116) antibodyHLA-DOB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HLA-DOB (Major Histocompatibility Complex, Class II, DO beta (HLA-DOB))
- 别名
- HLA-DOB (HLA-DOB 产品)
- 别名
- DOB antibody, major histocompatibility complex, class II, DO beta antibody, HLA-DOB antibody, PATR-DOB antibody
- 背景
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HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Alias Symbols: DOB
Protein Interaction Partner: HLA-DMB, CD82, CD63,
Protein Size: 273 - 分子量
- 30 kDa
- 基因ID
- 3112
- NCBI登录号
- NM_002120, NP_002111
- UniProt
- Q5QNS2
- 途径
- Cancer Immune Checkpoints
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