ATG5 抗体 (Middle Region)
Quick Overview for ATG5 抗体 (Middle Region) (ABIN2787927)
抗原
See all ATG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against ATG5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ATG5
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 275 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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别名
- ATG5
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背景
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ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Alias Symbols: APG5, APG5-LIKE, APG5L, ASP, hAPG5
Protein Interaction Partner: TEKT4, CCHCR1, WIPI2, KEAP1, VCP, MEOX2, FADD, ATG16L1, RB1CC1, EXOC4, ATG3, ATG12, CAV1, HTT, WDFY3, TAB3, TAB2, TECPR1, ELAVL1, UBC, SIRT1, TKT, MAP1LC3C, MAP1LC3B, ATG10, ATG5, IMPDH2,
Protein Size: 275 -
分子量
- 32 kDa
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基因ID
- 9474
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NCBI登录号
- NM_004849, NP_004840
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UniProt
- Q9H1Y0
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途径
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
抗原
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