ATG4B 抗体 (N-Term)
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- 抗原 See all ATG4B 抗体
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 兔, Cow, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATG4B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SVLNAFIDRK DSYYSIHQIA QMGVGEGKSI GQWYGPNTVA QVLKKLAVFD
- 预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against ATG4B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATG4B
- Top Product
- Discover our top product ATG4B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 393 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
- 别名
- ATG4B (ATG4B 产品)
- 背景
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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: APG4B, AUTL1, MGC1353
Protein Interaction Partner: SUMO2, MAP1LC3B, MAP1LC3A, BAG3, ATG8, YWHAB, GABARAPL1, SQSTM1, UBC, GABARAPL2, ATG10, ATG3, AMBRA1, GABARAP, CAMKK2, ATG12, ULK1, STK3, KRT4, ANXA1, FBXW11, LINC00341,
Protein Size: 393 - 分子量
- 44 kDa
- 基因ID
- 23192
- NCBI登录号
- NM_013325, NP_037457
- UniProt
- Q9Y4P1
- 途径
- Autophagy
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