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BAX 抗体 (N-Term)

BAX 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 犬, 绵羊, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787858
发货至: 中国
  • 抗原 See all BAX 抗体
    BAX (BCL2-Associated X Protein (BAX))
    抗原表位
    • 39
    • 32
    • 20
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    • 15
    • 11
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    N-Term
    适用
    • 258
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    • 9
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    人, 小鼠, 大鼠, Pig, Cow, 兔, 犬, 绵羊, 马, 豚鼠
    宿主
    • 169
    • 97
    • 4
    • 2
    克隆类型
    • 181
    • 91
    多克隆
    标记
    • 143
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    This BAX antibody is un-conjugated
    应用范围
    • 242
    • 114
    • 73
    • 66
    • 53
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    • 52
    • 45
    • 42
    • 14
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    Western Blotting (WB)
    序列
    IMKTGALLLQ GFIQDRAGRM GGEAPELALD PVPQDASTKK LSECLKRIGD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 91%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against BAX. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human BAX
    Top Product
    Discover our top product BAX Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 218 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    BAX (BCL2-Associated X Protein (BAX))
    别名
    BAX (BAX 产品)
    别名
    BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody
    背景
    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
    Alias Symbols: BCL2L4
    Protein Interaction Partner: CYCS, ZBTB24, UBC, CASP9, CASP8, CASP7, CASP3, BCL2L1, BCL2, CLU, MDM2, MCL1, BAX, BAG3, YWHAB, VCP, CRYAB, CRYAA, BAK1, XIAP, TP53, KCNA3, HSPA4, XRCC6, XRCC5, HDAC6, BAD, PSMC5, PSMC3, PARK7, UHRF2, RNF144B, OYE2, TOMM22, TOMM40, MEPCE, MOAP1, BBC3, PPP
    Protein Size: 218
    分子量
    24 kDa
    基因ID
    581
    NCBI登录号
    NM_004324, NP_004315
    UniProt
    Q07812
    途径
    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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