KAT2B 抗体 (C-Term)
Quick Overview for KAT2B 抗体 (C-Term) (ABIN2787454)
抗原
See all KAT2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PGLSCFKDGV RQIPIESIPG IRETGWKPSG KEKSKEPRDP DQLYSTLKSI
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预测反应
- Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against PCAF. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PCAF
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anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibody
KAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 1-142) antibodyKAT2B 适用: 人, 小鼠, 大鼠, 猴 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7D12C8 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 451-550) antibodyKAT2B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 583-832) antibodyKAT2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 832 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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别名
- PCAF
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背景
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CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-749 AC099057.3 17115-17863 750-876 AC099057.3 49416-49542 877-1022 AC099057.3 72346-72491 1023-1115 AC099057.3 76945-77037 1116-1297 AC099057.3 78370-78551 1298-1489 AC099057.3 88679-88870 1490-1596 AC099057.3 91965-92071 1597-1722 AC099057.3 96681-96806 1723-1859 AC099057.3 99751-99887 1860-2068 AC099057.3 102988-103196 2069-2195 AC099057.3 104506-104632 2196-2306 AC099057.3 114025-114135 2307-2450 AC099057.3 117304-117447 2451-2565 AC099057.3 123399-123513 2566-2602 AC099057.3 125046-125082 2603-2666 AC099057.3 125326-125389 2667-2751 AC099057.3 125486-125570 2752-4824 AC099057.3 129415-131487
Alias Symbols: CAF, KAT2B, P, P/CAF, PCAF
Protein Interaction Partner: MDM2, HNRNPD, ACLY, KLF2, E2F1, VHL, IRF1, TAL1, TAF12, TAF10, TAF9, TADA2A, RB1, HIST1H1B, TAF5L, TAF6L, TADA3, SUPT3H, TWIST1, PDK1, AKT1, UBC, SIAH2, UBE2D3, UBE2D1, TP73, TP53, SRC, PGR, YEATS2, MBIP, WDR5, PTEN, DR1, HIF1A, HIST2H3C, CHEK2, HIST1H4A,
Protein Size: 832 -
分子量
- 93 kDa
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基因ID
- 8850
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NCBI登录号
- NM_003884, NP_003875
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UniProt
- Q92831
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途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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