PSMD10 抗体 (N-Term)
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- 抗原 See all PSMD10 抗体
- PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, 兔, 犬, 豚鼠, 马, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMD10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KERILADKSL ATRTDQDSRT ALHWACSAGH TEIVEFLLQL GVPVNDKDDA
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against Psmd10. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product PSMD10 Primary Antibody
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anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 127-226) antibody
PSMD10 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B5 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) antibodyPSMD10 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-226) antibodyPSMD10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-226) antibodyPSMD10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-226) antibodyPSMD10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (C-Term) antibodyPSMD10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 23-72) antibodyPSMD10 适用: 人, 小鼠, 大鼠, 斑马鱼, 兔, 犬, 豚鼠, 马, Cow, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 43-76) antibodyPSMD10 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-226) antibodyPSMD10 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) antibodyPSMD10 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 231 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
- 别名
- Psmd10 (PSMD10 产品)
- 别名
- gankyrin antibody, zgc:109707 antibody, dJ889N15.2 antibody, p28 antibody, p28(GANK) antibody, AW554874 antibody, p28Gank antibody, proteasome 26S subunit, non-ATPase 10 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 antibody, psmd10 antibody, PSMD10 antibody, Psmd10 antibody
- 背景
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Psmd10 acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly,Psmd10 is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module By similarity.Psmd10 acts as an oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53. Overexpression of this gene is leading to phosphorylation of RB1 and proteasomal degradation of RB1. Psmd10 regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4.
Alias Symbols: AW554874
Protein Interaction Partner: Psmc4, Rb1, Cebpa, Cdk4,
Protein Size: 231 - 分子量
- 25 kDa
- 基因ID
- 53380
- NCBI登录号
- NM_016883, NP_058579
- UniProt
- Q9Z2X2
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Ubiquitin Proteasome Pathway
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