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PSMD10 抗体 (AA 43-76)

PSMD10 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5536458
发货至: 中国
  • 抗原 See all PSMD10 抗体
    PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
    抗原表位
    • 9
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 43-76
    适用
    • 40
    • 10
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 35
    • 5
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD10 antibody is un-conjugated
    应用范围
    • 27
    • 19
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PSMD10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 43-76 amino acids from the Central region of human PSMD10.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PSMD10 Primary Antibody
  • 应用备注
    For IF starting dilution is: 1:25

    For IHC-P starting dilution is: 1:25

    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.48 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
    别名
    PSMD10 (PSMD10 产品)
    别名
    gankyrin antibody, zgc:109707 antibody, dJ889N15.2 antibody, p28 antibody, p28(GANK) antibody, AW554874 antibody, p28Gank antibody, proteasome 26S subunit, non-ATPase 10 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 antibody, psmd10 antibody, PSMD10 antibody, Psmd10 antibody
    背景
    Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pahway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.
    分子量
    24 kDa
    基因ID
    5716
    UniProt
    O75832
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Ubiquitin Proteasome Pathway
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