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LCK 抗体 (N-Term)

Name: LCK 抗体 (N-Term)
SKU: ABIN311701
Availability: OutOfStock

LCK 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-LCK Antibody Titration: 0. (LCK 抗体 (N-Term))

1 image

产品编号 ABIN311701

发货至: 中国

Datasheet as PDF

抗原 See all LCK 抗体

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
抗原表位
24

16

15

11

10

8

8

8

7

5

5

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
163

95

60

9

6

6

4

4

4

3

3

2

1
人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠
宿主
147

14

2
兔
Compatible Secondaries
克隆类型
147

17
多克隆
标记
95

10

9

7

5

4

4

4

4

4

4

4

2

2

2

2

2
This LCK antibody is un-conjugated
应用范围
128

88

29

25

23

19

15

14

13

9

3

3

2

1

1

1
Western Blotting (WB)

序列

PSHDGDLGFE KGEQLRILEQ SGEWWKAQSL TTGQEGFIPF NFVAKANSLE

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%

产品特性

This is a rabbit polyclonal antibody against LCK. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human LCK

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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibody
LCK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibody
LCK 适用: 人 WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal LCK-01 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibody
LCK 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibody
LCK 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-100) antibody
LCK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 509 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

别名

LCK (LCK 产品)

别名

zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56 antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody

背景

LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Alias Symbols: YT16, p56lck, pp58lck, LSK
Protein Interaction Partner: LZTS2, CDKAL1, BAG6, UBC, WASL, WAS, env, SMAD3, SMAD2, MAPK1, HSP90AA1, Mbp, HAVCR2, PTPN22, G3BP1, nef, LAT, KHDRBS1, ADAM15, ZAP70, PAK2, LCK, CBL, SOCS3, SOCS2, SOCS1, IL2RB, CISH, YWHAQ, AJUBA, CD5, CBLB, SKAP1, SYK, SOS1, CD38, CD247, CD3E, FAM174A,
Protein Size: 509

分子量

58 kDa

基因ID

3932

NCBI登录号

NM_001042771, NP_001036236

UniProt

P06239

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling