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PACS2 抗体 (Middle Region)

PACS2 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784562
发货至: 中国
  • 抗原 See all PACS2 抗体
    PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
    抗原表位
    • 8
    • 6
    • 5
    • 4
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    This PACS2 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 12
    • 3
    • 1
    Western Blotting (WB)
    序列
    AHQLPIAEAM LTYKQKSPDE ESSQKFIPFV GVVKVGIVEP SSATSGDSDD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against PACS2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PACS2
    Top Product
    Discover our top product PACS2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 889 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
    别名
    PACS2 (PACS2 产品)
    别名
    PACS-2 antibody, PACS1L antibody, 6720425G15Rik antibody, AW208651 antibody, AW489976 antibody, E230011J22 antibody, Pacs1l antibody, mKIAA0602 antibody, phosphofurin acidic cluster sorting protein 2 antibody, PACS2 antibody, Pacs2 antibody
    背景
    PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
    Alias Symbols: FLJ25488, KIAA0602, PACS1L, PACS-2
    Protein Interaction Partner: UBC, TRAF2, BIRC3, BIRC2, PKD2, BID,
    Protein Size: 889
    分子量
    98 kDa
    基因ID
    23241
    NCBI登录号
    NM_015197, NP_056012
    UniProt
    Q86VP3
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