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PACS2 产品

(phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Categories

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

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Featured PACS2 Categories

PACS2 抗体

High quality antibodies with extensive validation data.

PACS2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PACS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7163270
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN657066
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7163273
Quantity 100 μg
Datasheet Datasheet

Recommended PACS2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233897
Quantity 96 tests
Datasheet Datasheet

Recommended PACS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313862
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094328
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135128
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PACS2 Products

Aslan, You, Williamson, Endig, Youker, Thomas, Shu, Du, Milewski, Brush, Possemato, Sprott, Fu, Greis, Runckel, Vogel, Thomas: "Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis." in: Molecular cell, Vol. 34, Issue 4, pp. 497-509, (2009) (PubMed).

Synonyms and alternative names related to PACS2

phosphofurin acidic cluster sorting protein 2 (PACS2), phosphofurin acidic cluster sorting protein 2 (Pacs2), 6720425G15Rik, AW208651, AW489976, E230011J22, mKIAA0602, PACS-2, PACS1L, Pacs1l

Protein level used designations for PACS2

  • PACS1-like protein
  • PACS-2
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