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MAP3K1 抗体 (C-Term)

This 兔 多克隆 anti-MAP3K1 antibody specifically detects MAP3K1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 斑马鱼 和 犬 samples.
产品编号 ABIN2783464
发货至: 中国
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Quick Overview for MAP3K1 抗体 (C-Term) (ABIN2783464)

抗原

See all MAP3K1 抗体
MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

适用

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人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 斑马鱼, 犬

宿主

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克隆类型

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多克隆

标记

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This MAP3K1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    LGAFSSCYQA QDVGTGTLMA VKQVTYVRNT SSEQEEVVEA LREEIRMMSH

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against MAP3K1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1512 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

    别名

    MAP3K1

    背景

    MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-983 AC008937.7 118022-119004 c 984-1536 AF042838.1 426-978 1537-1653 AC008937.7 68621-68737 c 1654-1802 AC008937.7 68100-68248 c 1803-2870 AF042838.1 1245-2312 2871-4167 AC008937.7 51211-52507 c 4168-4758 BU194120.1 127-717 4759-5154 DA889202.1 164-559 5155-7355 AC008937.7 38082-40282 c 7356-7522 AA602425.1 1-167 c
    Alias Symbols: MAPKKK1, MEKK, MEKK1, SRXY6
    Protein Interaction Partner: MAP2K4, CHUK, IKBKB, UBC, BRCA1, TRIM5, STK38, KAT5, SUMO1, RHOA, HIPK2, CRTC1, YWHAQ, DCAF7, DYRK1B, YWHAG, TRAF2, TP53, MAP4K2, MAP2K7, MAP2K1, MAPK9, MAPK8, MAPK1, PAK1, NFKBIA, MAP3K1, JUN, NR4A1, GSTP1, GSK3B, DYRK1A, UBE2I, FLNB, Axin1, ARHGAP4, ACT
    Protein Size: 1512

    分子量

    164 kDa

    基因ID

    4214

    NCBI登录号

    NM_005921, NP_005912

    UniProt

    Q13233

    途径

    MAPK Pathway, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
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