PVRL2 抗体 (Middle Region)
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- 抗原 See all PVRL2 抗体
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PVRL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MEPDGKDEEE EEEEEKAEKG LMLPPPPALE DDMESQLDGS LISRRAVYV
- 预测反应
- Human: 100%, Mouse: 93%, Pig: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PVRL2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PVRL2
- Top Product
- Discover our top product PVRL2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 479 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- 别名
- PVRL2 (PVRL2 产品)
- 别名
- prr2 antibody, AI325026 antibody, AI987993 antibody, Cd112 antibody, MPH antibody, Pvr antibody, Pvs antibody, nectin-2 antibody, CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, nectin cell adhesion molecule 2 antibody, Nectin2 antibody, NECTIN2 antibody
- 背景
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This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD112, HVEB, PRR2, PVRR2
Protein Interaction Partner: KRTAP10-3, KRTAP10-5, KRTAP10-1, KRTAP10-7, NOTCH2NL, SIAH1, MDFI, KRTAP5-9, TIGIT, PVRL4, TNFRSF12A, PVRL3, PVRL2, LYRM4, DUS2, USP53, UBC, MAPK6, ATP5J2, PICK1, CD226, MLLT4,
Protein Size: 479 - 分子量
- 48 kDa
- 基因ID
- 5819
- NCBI登录号
- NM_002856, NP_002847
- UniProt
- Q0MSE5
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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