MTHFD1 抗体 (Middle Region)
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- 抗原 See all MTHFD1 抗体
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 兔, 马, 斑马鱼, Pig, 犬, 豚鼠, Cow, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTHFD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- CMAKTHLSLS HNPEQKGVPT GFILPIRDIR ASVGAGFLYP LVGTMSTMPG
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against MTHFD1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MTHFD1
- Top Product
- Discover our top product MTHFD1 Primary Antibody
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anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 1-935) antibody
MTHFD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 1-935) antibodyMTHFD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) antibodyMTHFD1 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 535-562) antibodyMTHFD1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19391 unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) antibodyMTHFD1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (Internal Region) antibodyVerified MTHFD1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 863-912) antibodyMTHFD1 适用: 人, 小鼠, 大鼠, 兔, 马, 斑马鱼, Pig, 犬, 豚鼠, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 74-123) antibodyMTHFD1 适用: 人, 小鼠, 大鼠, 兔, 斑马鱼, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (AA 1-270) antibodyMTHFD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (N-Term) antibodyMTHFD1 适用: 人, 小鼠, 大鼠, 兔, 马, 斑马鱼, 犬, 豚鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 935 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- 别名
- MTHFD1 (MTHFD1 产品)
- 别名
- MTHFC antibody, MTHFD antibody, Tb07.27M11.970 antibody, Dcs antibody, E430024A07Rik antibody, Mthfd antibody, GB13160 antibody, cb325 antibody, fc29f07 antibody, mthfd1 antibody, wu:fc29f07 antibody, zgc:55597 antibody, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 antibody, C-1-tetrahydrofolate synthase, cytoplasmic antibody, putative C-1-tetrahydrofolate synthase, cytoplasmic antibody, putative C-1-tetrahydrofolate synthase,cytoplasmic antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b antibody, c-1-tetrahydrofolate synthase, cytoplasmic antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase antibody, MTHFD1 antibody, Mthfd1 antibody, Tc00.1047053509509.20 antibody, Tc00.1047053511741.50 antibody, Tc00.1047053511517.60 antibody, Tc00.1047053508207.240 antibody, Tb927.7.1600 antibody, LINJ_26_0310 antibody, LBRM_26_0350 antibody, LMJF_26_0320 antibody, mthfd1l antibody, LOC550749 antibody, mthfd1b antibody, Tsp_00651 antibody, mthfd1.L antibody, mthfd1 antibody, LOC589933 antibody, LOC100634307 antibody
- 背景
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MTHFD1 possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MTHFC, MTHFD
Protein Interaction Partner: UBC, FUS, SUMO2, SUMO3, NEDD8, MDM2, RPA3, RPA2, RPA1, RNF2, RPS21, MAT2A, UBQLN1, FBXO6, UBD, ADRB2, CD81, VCAM1, HSP90AA1, HSP90AB1, PRKCDBP, SFXN1, TMEM165, IARS2, SARS2, SF3B3, FAF2, PPT2, SNRNP70, RPL32, MRPL23, ALDH18A1, PRPH, PC, ICT1, GAA, ACSL3,
Protein Size: 935 - 分子量
- 101 kDa
- 基因ID
- 4522
- NCBI登录号
- NM_005956, NP_005947
- UniProt
- P11586
- 途径
- Methionine Biosynthetic Process
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