PTPN2 抗体 (N-Term)
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- 抗原 See all PTPN2 抗体
- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, 兔, 豚鼠, 马, 犬, Cow, 斑马鱼, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LEIRNESHDY PHRVAKFPEN RNRNRYRDVS PYDHSRVKLQ NAENDYINAS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against PTPN2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PTPN2
- Top Product
- Discover our top product PTPN2 Primary Antibody
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-353) antibody
PTPN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-257) antibodyPTPN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-387) antibodyPTPN2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 201-250) antibodyPTPN2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 马, 犬, Cow, 斑马鱼, 猴, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (C-Term) antibodyPTPN2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-330) antibodyPTPN2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 329-358), (C-Term) antibodyPTPN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33304 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) antibodyPTPN2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 353 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
- 别名
- PTPN2 (PTPN2 产品)
- 别名
- PTN2 antibody, PTPT antibody, TC-PTP antibody, TCELLPTP antibody, TCPTP antibody, AI325124 antibody, Ptpt antibody, PTP-1B antibody, cb806 antibody, ptpn2 antibody, ptpn2l antibody, wu:fc10h07 antibody, zgc:55339 antibody, zgc:76973 antibody, hm:zeh1546 antibody, zgc:63623 antibody, ptn2 antibody, ptpt antibody, tc-ptp antibody, tcellptp antibody, tcptp antibody, protein tyrosine phosphatase, non-receptor type 2 antibody, protein tyrosine phosphatase, non-receptor type 2 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 2, b antibody, protein tyrosine phosphatase, non-receptor type 2, a antibody, protein tyrosine phosphatase, non-receptor type 2 L homeolog antibody, PTPN2 antibody, Ptpn2 antibody, ptpn2.S antibody, ptpn2b antibody, ptpn2a antibody, ptpn2.L antibody
- 背景
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PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported.
Alias Symbols: PTPT, TC-PTP, TCELLPTP, TCPTP, PTN2
Protein Interaction Partner: UBC, BAG3, STAT1, STAT6, KATNB1, HSPD1, TRAF2, SRC, GHR, UCHL5, FKBP4, STAT5B, KPNB1, STAT5A, SHC1, JAK3, ITGA1, PDGFRB, JAK1, INSR, EGFR, CDK5, CDK2, CDK1, STAT3, SFN,
Protein Size: 353 - 分子量
- 39 kDa
- 基因ID
- 5771
- NCBI登录号
- NM_080423, NP_536348
- UniProt
- Q96AU5
- 途径
- EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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