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NR1H3 抗体 (C-Term)

NR1H3 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780709
发货至: 中国
  • 抗原 See all NR1H3 抗体
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    抗原表位
    • 16
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 76
    • 55
    • 44
    • 17
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 兔, 豚鼠, 斑马鱼
    宿主
    • 84
    • 9
    • 2
    克隆类型
    • 77
    • 18
    多克隆
    标记
    • 43
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NR1H3 antibody is un-conjugated
    应用范围
    • 81
    • 31
    • 27
    • 27
    • 27
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    IHHPHDRLMF PRMLMKLVSL RTLSSVHSEQ VFALRLQDKK LPPLLSEIWD
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against NR1H3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human NR1H3
    Top Product
    Discover our top product NR1H3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 447 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Torra, Ismaili, Feig, Xu, Cavasotto, Pancratov, Rogatsky, Neubert, Fisher, Garabedian: "Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages." in: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2626-36, (2008) (PubMed).

  • 抗原
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    别名
    NR1H3 (NR1H3 产品)
    别名
    NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
    背景
    Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
    Alias Symbols: LXR-a, LXRA, RLD-1
    Protein Interaction Partner: RXRG, RXRB, MDFI, SUV39H1, KDM1A, BARD1, MSTO1, HSP90AA1, PIAS1, APP, NR3C1, MYC, ZXDC, TMEM161A, ING3, NCOA6, NCOR1, KAT2B, EIF3I, NRIP1, NCOA3, SRC, RXRA, FOXO3, ACTN1, SS18L1, LZTR1, EDF1, RARA, NR0B2, SYT1, PPARA, SIRT1, UBC, CEP350,
    Protein Size: 447
    分子量
    50 kDa
    基因ID
    10062
    NCBI登录号
    NM_005693, NP_005684
    UniProt
    Q13133
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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