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- 抗原 See all ELF3 抗体
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TATPQSSHAS DSGGSDVDLD LTESKVFPRD GFPDYKKGEP KHGKRKRGRP
- 预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 92%, Human: 77%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Elf3. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product ELF3 Primary Antibody
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anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 1-280) antibody
ELF3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 1-280) antibodyELF3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 262-371) antibodyELF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (C-Term) antibodyELF3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (N-Term) antibodyELF3 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 147-371) antibodyELF3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (C-Term) antibodyVerified ELF3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (N-Term) antibodyELF3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人 WB, ChIP 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 371 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
- 别名
- Elf3 (ELF3 产品)
- 别名
- ert antibody, esx antibody, epr-1 antibody, ese-1 antibody, ESE-1 antibody, ESX antibody, jen antibody, EPR-1 antibody, ERT antibody, E74 like ETS transcription factor 3 antibody, E74-like factor 3 antibody, elf3 antibody, Elf3 antibody, ELF3 antibody
- 背景
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Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Elf3 acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter.Elf3 also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Elf3 represses KRT4 promoter activity.Elf3 is involved in mediating vascular inflammation. Elf3 may play an important role in epithelial cell differentiation and tumorigenesis. Elf3 may be a critical downstream effector of the ERBB2 signaling pathway. Elf3 may be associated with mammary gland development and involution. Elf3 plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Alias Symbols: ESE-1, ESX, jen
Protein Size: 371 - 分子量
- 42 kDa
- 基因ID
- 13710
- NCBI登录号
- NM_007921, NP_031947
- UniProt
- Q3UPW2
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