ELF3 抗体 (N-Term)
(1 reference)-
- 抗原 See all ELF3 抗体
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
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抗原表位
- N-Term
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适用
- 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MAATCEISNV FSNYFNAMYS SEDPTLAPAP PTTFGTEDLV LTLNNQQMTL
- 预测反应
- Mouse: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Elf3. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse Elf3
- Top Product
- Discover our top product ELF3 Primary Antibody
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anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 1-280) antibody
ELF3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 1-280) antibodyELF3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 262-371) antibodyELF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (C-Term) antibodyELF3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 147-371) antibodyELF3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (C-Term) antibodyVerified ELF3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (N-Term) antibodyELF3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人 WB, ChIP 宿主: 兔 Monoclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 371 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking." in: Analytical biochemistry, Vol. 383, Issue 2, pp. 265-9, (2008) (PubMed).
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: "A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking." in: Analytical biochemistry, Vol. 383, Issue 2, pp. 265-9, (2008) (PubMed).
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- 抗原
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
- 别名
- Elf3 (ELF3 产品)
- 别名
- ert antibody, esx antibody, epr-1 antibody, ese-1 antibody, ESE-1 antibody, ESX antibody, jen antibody, EPR-1 antibody, ERT antibody, E74 like ETS transcription factor 3 antibody, E74-like factor 3 antibody, elf3 antibody, Elf3 antibody, ELF3 antibody
- 背景
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Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Alias Symbols: ESE-1, ESX, jen
Protein Size: 371 - 分子量
- 41 kDa
- 基因ID
- 13710
- NCBI登录号
- NM_007921, NP_031947
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