CrkL 抗体 (Middle Region)
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- 抗原 See all CrkL (CRKL) 抗体
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CrkL antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
- 产品特性
- This is a rabbit polyclonal antibody against CRKL. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human CRKL
- Top Product
- Discover our top product CRKL Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 303 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
- 别名
- CRKL (CRKL 产品)
- 别名
- CRKL antibody, wu:fa55g05 antibody, wu:fj60e01 antibody, zgc:63469 antibody, 1110025F07Rik antibody, AA589403 antibody, AI325100 antibody, Crkol antibody, CRK like proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog-like antibody, CRKL antibody, crkl antibody, Crkl antibody
- 背景
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CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
Alias Symbols: -
Protein Interaction Partner: HUWE1, UBC, BAG3, PIK3R2, DOK1, CBL, LMNA, SHANK3, GAREM, BIK, AOX1, WAC, POLR1D, TENC1, KHDRBS1, PPFIBP2, ARHGEF5, YY1, RPL31, ERBB3, ERBB2, PHC2, BCAR1, RAPGEF1, EPS15, EGFR, ABL1, STAT5A, PIK3R1, EPOR, ELAVL1, MSL1, PLEKHA1, LTBP4, PLSCR1, NOTCH2, LAMA
Protein Size: 303 - 分子量
- 34 kDa
- 基因ID
- 1399
- NCBI登录号
- NM_005207, NP_005198
- UniProt
- P46109
- 途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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