BCL2L1 抗体 (N-Term)
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北京 101111
Quick Overview for BCL2L1 抗体 (N-Term) (ABIN2779336)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- BCL2L1 Antibody - N-terminal region
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序列
- SNRELVVDFL SYKLSQKGYS WSQFSDVEEN RTEAPEGTES EMETPSAING
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against BCL2L1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2L1
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anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibody
BCL2L1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) antibodyBCL2L1 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibodyBCL2L1 适用: 人 WB, IF, ELISA, PLA 宿主: 小鼠 Monoclonal 3E2-2A5 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 IHC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-219) antibodyBCL2L1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibodyBCL2L1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 81-200) antibodyBCL2L1 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-209) antibodyBCL2L1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095471
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- BCL2L1
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背景
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Background Information: BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Gene Name: BCL2-like 1
Alternative Symbols: BCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S
Protein Name: Bcl-2-like protein 1
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分子量
- 26kDa
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基因ID
- 598
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NCBI登录号
- NP_612815
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UniProt
- Q07817
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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