BAD 抗体 (C-Term)
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Quick Overview for BAD 抗体 (C-Term) (ABIN2779324)
抗原
See all BAD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RMSDEFVDSF KKGLPRPKSA GTATQMRQSS SWTRVFQSWW DRNLGRGSSA
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预测反应
- Cow: 100%, Dog: 90%, Guinea Pig: 100%, Horse: 90%, Human: 100%, Mouse: 100%, Pig: 90%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against BAD. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human BAD
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anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 101-204) antibody
BAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1G5B3 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer136) antibodyBAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer155) antibodyBAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 69-168) antibodyBAD 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibodyBAD 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibodyBAD 适用: 人 ELISA, IHC, DB, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 53-81) antibodyBAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06939 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 168 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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别名
- BAD
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背景
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BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Alias Symbols: BBC2, BCL2L8
Protein Interaction Partner: BCL2L1, BCL2, AKT1, PAK1, BMH1, YWHAB, SFN, YWHAZ, RAF1, PRKACA, BRAF, ARAF, CREB3L3, STEAP3, YWHAQ, KEAP1, YWHAH, YWHAE, PRDX2, CDKN1A, VCP, SNCA, PPP1CA, BAX, SUMO2, YWHAG, PIM3, MCL1, RPS6KA5, PAK7, BCL2L10, WASF1, HRK, MAP2K5, BCL2L2, RPS6KA2, RPS6KA1
Protein Size: 168 -
分子量
- 18 kDa
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基因ID
- 572
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NCBI登录号
- NM_004322, NP_004313
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UniProt
- Q92934
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途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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