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BAD 抗体 (Middle Region)

This anti-BAD antibody is a 兔 多克隆 antibody detecting BAD in WB. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 豚鼠 和 马. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2779311
发货至: 中国

Quick Overview for BAD 抗体 (Middle Region) (ABIN2779311)

抗原

See all BAD 抗体
BAD (BCL2-Associated Agonist of Cell Death (BAD))

适用

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人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This BAD antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    Middle Region

    序列

    GAVEIRSRHS SYPAGTEDDE GMGEEPSPFR GRSRSAPPNL WAAQRYGREL

    预测反应

    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against BAD. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 168 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mishra, Thakur, Somal, Parmar, Yadav, Bharati, Bharti, Paul, Verma, Chouhan, Sharma, Singh, González, DOcchio, Sarkar et al.: "Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured ..." in: Theriogenology, Vol. 86, Issue 7, pp. 1818-33, (2016) (PubMed).

    Mishra, Parmar, Yadav, Reshma, Bharati, Bharti, Paul, Chouhan, Taru Sharma, Singh, Sarkar et al.: "Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability ..." in: Reproduction in domestic animals = Zuchthygiene, Vol. 51, Issue 6, pp. 855-869, (2016) (PubMed).

  • 抗原

    BAD (BCL2-Associated Agonist of Cell Death (BAD))

    别名

    BAD

    背景

    The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
    Alias Symbols: BBC2, BCL2L8
    Protein Interaction Partner: BCL2L1, BCL2, AKT1, PAK1, BMH1, YWHAB, SFN, YWHAZ, RAF1, PRKACA, BRAF, ARAF, CREB3L3, STEAP3, YWHAQ, KEAP1, YWHAH, YWHAE, PRDX2, CDKN1A, VCP, SNCA, PPP1CA, BAX, SUMO2, YWHAG, PIM3, MCL1, RPS6KA5, PAK7, BCL2L10, WASF1, HRK, MAP2K5, BCL2L2, RPS6KA2, RPS6KA1
    Protein Size: 168

    分子量

    18 kDa

    基因ID

    572

    NCBI登录号

    NM_004322, NP_004313

    UniProt

    Q92934

    途径

    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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