DROSHA 抗体 (Middle Region)
-
- 抗原 See all DROSHA 抗体
- DROSHA (Drosha, Ribonuclease Type III (DROSHA))
-
抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, Cow, 马
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DROSHA antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- AAMDALEKYN FPQMAHQKRF IERKYRQELK EMRWEREHQE REPDETEDIK
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against RNASEN. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RNASEN
- Top Product
- Discover our top product DROSHA Primary Antibody
-
anti-Drosha, Ribonuclease Type III (DROSHA) (Internal Region) antibody
DROSHA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) antibodyDROSHA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) (C-Term) antibodyDROSHA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) (Internal Region) antibodyVerified DROSHA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) antibodyDROSHA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) (AA 124-151) antibodyDROSHA 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) (AA 1114-1235) antibodyDROSHA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) (AA 1-100) antibodyDROSHA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) antibodyDROSHA 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Drosha, Ribonuclease Type III (DROSHA) (C-Term) antibodyDROSHA 适用: 人, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 1374 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- DROSHA (Drosha, Ribonuclease Type III (DROSHA))
- 别名
- RNASEN (DROSHA 产品)
- 别名
- im:7150667 antibody, zgc:158612 antibody, ETOHI2 antibody, HSA242976 antibody, RANSE3L antibody, RN3 antibody, RNASE3L antibody, RNASEN antibody, 1110013A17Rik antibody, AI874853 antibody, Etohi2 antibody, Rn3 antibody, Rnasen antibody, RGD1307626 antibody, ribonuclease type III, nuclear antibody, Ribonuclease 3 antibody, ribonuclease 3 antibody, drosha ribonuclease III antibody, drosha, ribonuclease type III antibody, rnasen antibody, Thicy_0885 antibody, Sinme_0866 antibody, Isova_2087 antibody, Sphch_0770 antibody, DROSHA antibody, Drosha antibody
- 背景
-
RNASEN is a ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, RNASEN/DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. RNASEN is also involved in pre-rRNA processing. RNASEN cleaves double-strand RNA and does not cleave single-strand RNA. RNASEN is involved in the formation of GW bodies.Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM].
Alias Symbols: DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L, RNASEN
Protein Interaction Partner: DDX5, HNRNPUL2, KLHL12, YLPM1, ZCCHC8, DGCR8, SKIV2L2, U2SURP, KHDRBS1, CARM1, RBM14, PDCD6, THRAP3, PPFIA1, SRPK1, PKP2, MEN1, LGALS3BP, HNRNPAB, WWOX, BMI1, SRPK2, ZNF512B, UBC, CUL3, PSMA1, BCL6, SP1,
Protein Size: 1374 - 分子量
- 159 kDa
- 基因ID
- 29102
- NCBI登录号
- NM_013235, NP_037367
- UniProt
- Q9NRR4
- 途径
- Regulatory RNA Pathways
-
