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DROSHA 抗体

DROSHA 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7244810
发货至: 中国
  • 抗原 See all DROSHA 抗体
    DROSHA (Drosha, Ribonuclease Type III (DROSHA))
    适用
    • 54
    • 17
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 53
    • 1
    • 1
    克隆类型
    • 45
    • 10
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    This DROSHA antibody is un-conjugated
    应用范围
    • 29
    • 17
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human DROSHA
    亚型
    IgG
    Top Product
    Discover our top product DROSHA Primary Antibody
  • 应用备注
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.74 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DROSHA (Drosha, Ribonuclease Type III (DROSHA))
    别名
    DROSHA (DROSHA 产品)
    别名
    im:7150667 antibody, zgc:158612 antibody, ETOHI2 antibody, HSA242976 antibody, RANSE3L antibody, RN3 antibody, RNASE3L antibody, RNASEN antibody, 1110013A17Rik antibody, AI874853 antibody, Etohi2 antibody, Rn3 antibody, Rnasen antibody, RGD1307626 antibody, ribonuclease type III, nuclear antibody, Ribonuclease 3 antibody, ribonuclease 3 antibody, drosha ribonuclease III antibody, drosha, ribonuclease type III antibody, rnasen antibody, Thicy_0885 antibody, Sinme_0866 antibody, Isova_2087 antibody, Sphch_0770 antibody, DROSHA antibody, Drosha antibody
    背景
    This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. DROSHA (Drosha Ribonuclease III) is a Protein Coding gene. Diseases associated with DROSHA include Combat Disorder and Murray Valley Encephalitis. Among its related pathways are mRNA Capping and Gene Expression. GO annotations related to this gene include poly(A) RNA binding and RNA binding.
    UniProt
    Q9NRR4
    途径
    Regulatory RNA Pathways
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