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LBP 抗体 (C-Term)

Name: LBP 抗体 (C-Term)
SKU: ABIN2776869
Availability: OutOfStock

LBP 适用: 人, Cow, Pig, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-LBP Antibody Titration: 0.

Rabbit Anti-LBP Antibody Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm and plasma membrane in endothelial cells in sinusoids Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.

IHC

LBP antibody - C-terminal region Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cell membrane in endothelial cell in sinusoids Primary Antibody Concentration: 1:100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.

IHC

3 images

产品编号 ABIN2776869

发货至: 中国

Datasheet as PDF

抗原 See all LBP 抗体

LBP (Lipopolysaccharide Binding Protein (LBP))
抗原表位
6

5

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
38

20

17

8

7

6

3

3

3

2

2
人, Cow, Pig, 马
宿主
44

19

5

2
兔
Compatible Secondaries
克隆类型
46

24
多克隆
标记
56

7

3

3

1
This LBP antibody is un-conjugated
应用范围
46

28

23

17

10

9

8

5

4

3

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

FLKPGKVKVE LKESKVGLFN AELLEALLNY YILNTFYPKF NDKLAEGFPL

预测反应

Cow: 86%, Horse: 85%, Human: 100%, Pig: 79%

产品特性

This is a rabbit polyclonal antibody against LBP. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human LBP

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LBP 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal biG42 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 481 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

LBP (Lipopolysaccharide Binding Protein (LBP))

别名

LBP (LBP 产品)

别名

BPIFD2 antibody, Bpifd2 antibody, Ly88 antibody, LPSBP antibody, LBP antibody, lipopolysaccharide binding protein antibody, lipopolysaccharide-binding protein antibody, LBP antibody, Lbp antibody, LOC100472839 antibody

背景

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
Alias Symbols: MGC22233, BPIFD2
Protein Interaction Partner: TSC22D4, PYCRL, TRA2A, PRDX4, SETD1A, CBFA2T2, BAG6, PSMA3, SMAD3, HSPB1, FTH1, C4BPA, BST1, CAMP, APOA1, RPS21, CD14, CFHR1, IRF6,
Protein Size: 481

分子量

53 kDa

基因ID

3929

NCBI登录号

NM_004139, NP_004130

UniProt

P18428

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process