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LBP 抗体 (C-Term)

The 兔多克隆 anti-LBP antibody (ABIN2776869) specifically detects LBP in WB 和 IHC. The antibody is reactive with 人, Cow, Pig 和马 samples.

Rabbit Anti-LBP Antibody Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm and plasma membrane in endothelial cells in sinusoids Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (LBP 抗体 (C-Term))

IHC

LBP antibody - C-terminal region Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cell membrane in endothelial cell in sinusoids Primary Antibody Concentration: 1:100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (LBP 抗体 (C-Term))

IHC

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产品编号 ABIN2776869

发货至: 中国

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中国
北京 101111

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Quick Overview for LBP 抗体 (C-Term) (ABIN2776869)

抗原

See all LBP 抗体

LBP (Lipopolysaccharide Binding Protein (LBP))

适用

人, Cow, Pig, 马

宿主

兔

克隆类型

多克隆

标记

This LBP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product LBP Primary Antibody

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C-Term

原理

LBP Antibody - C-terminal region

序列

FLKPGKVKVE LKESKVGLFN AELLEALLNY YILNTFYPKF NDKLAEGFPL

预测反应

Cow: 86%, Horse: 85%, Human: 100%, Pig: 79%

产品特性

This is a rabbit polyclonal antibody against LBP. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human LBP
anti-Lipopolysaccharide Binding Protein (LBP) (AA 226-480) antibody
LBP 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) (AA 224-468) antibody
LBP 适用: Cow WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) antibody
LBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) (AA 25-481) antibody
LBP 适用: 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) antibody
LBP 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG35 unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) antibody
LBP 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG33 unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) antibody
LBP 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal biG42 unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibody
LBP 适用: 人 IHC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) antibody
LBP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibody
LBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104521

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

LBP (Lipopolysaccharide Binding Protein (LBP))

别名

LBP

背景

Background Information: LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
Gene Name: Lipopolysaccharide binding protein
Alternative Symbols: BPIFD2
Protein Name: Lipopolysaccharide-binding protein

分子量

53 kDa

基因ID

3929

NCBI登录号

NP_004130

UniProt

P18428

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process