MBNL2 抗体 (Middle Region)
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- 抗原 See all MBNL2 抗体
- MBNL2 (Muscleblind-Like 2 (MBNL2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBNL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IACFDSLKGR CSRENCKYLH PPTHLKTQLE INGRNNLIQQ KTAAAMLAQQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Mbnl2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of RAT Mbnl2
- Top Product
- Discover our top product MBNL2 Primary Antibody
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anti-Muscleblind-Like 2 (MBNL2) (Middle Region) antibody
MBNL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-Like 2 (MBNL2) (AA 261-290), (C-Term) antibodyMBNL2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB32800 unconjugated
anti-Muscleblind-Like 2 (MBNL2) (AA 260-290), (C-Term) antibodyMBNL2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-Like 2 (MBNL2) (AA 46-95) antibodyMBNL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, Bat, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-Like 2 (MBNL2) (AA 160-260) antibodyMBNL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MBNL2 (Muscleblind-Like 2 (MBNL2))
- 别名
- Mbnl2 (MBNL2 产品)
- 别名
- 1110002M11Rik antibody, AI047808 antibody, AI837313 antibody, AI849185 antibody, AL118326 antibody, MBLL antibody, R75232 antibody, mKIAA4072 antibody, wu:fj89c04 antibody, MBLL39 antibody, PRO2032 antibody, muscleblind like splicing factor 2 antibody, muscleblind-like splicing regulator 2 antibody, muscleblind like splicing regulator 2 antibody, Mbnl2 antibody, mbnl2 antibody, MBNL2 antibody
- 背景
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Mbnl2 mediates pre-mRNA alternative splicing regulation. It acts either as activator or repressor of splicing on specific pre-mRNA targets. It inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. It antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. It seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques. It may play a role in myotonic dystrophy pathophysiology (DM).
Protein Size: 378 - 分子量
- 41 kDa
- 基因ID
- 680445
- UniProt
- F2Z3T4
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